A simple one-pot method for the synthesis of partially protected mono- and disaccharide building blocks using an orthoesterification–benzylation–orthoester rearrangement approach

A simple one-pot method is reported for making partially protected glycosyl acceptors from O-methyl or S-alkyl/aryl glycosides of d-glucose, d-galactose, d-arabinose, l-rhamnose, l-fucose and lactose via orthoester formation, benzylation and selective hydrolysis.