Title of article
Sialylation using N-glycolylneuraminyl phosphite donors to synthesize Neu5Gc-containing glycans Original Research Article
Author/Authors
Shinya Hanashima، نويسنده , , Taku Tomiya، نويسنده , , Daichi Ishikawa، نويسنده , , Shoji Akai، نويسنده , , Ken-ichi Sato، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2009
Pages
7
From page
959
To page
965
Abstract
Efficient sialylations using N-glycolylneuraminic acid (Neu5Gc) phosphite donors having an acetyl or benzyl group on the glycolyl moiety are described in the synthesis of Neu5Gc-containing glycans. Both phosphite donors 1 and 2 were readily coupled with primary and secondary acceptor alcohols in propionitrile at −78 °C to provide the desired glycosides with good α-selectivities.
Keywords
Glycosylation , N-Glycolylneuraminic acid , Sialic acid , Phosphite
Journal title
Carbohydrate Research
Serial Year
2009
Journal title
Carbohydrate Research
Record number
966403
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