• Title of article

    Chelation-controlled regioselective alkylation of pyrimidine 2′-deoxynucleosides Original Research Article

  • Author/Authors

    R. Lucas، نويسنده , , K. Teste، نويسنده , , R. Zerrouki، نويسنده , , Y. Champavier، نويسنده , , M. Guilloton، نويسنده ,

  • Issue Information
    دوهفته نامه با شماره پیاپی سال 2010
  • Pages
    9
  • From page
    199
  • To page
    207
  • Abstract
    Protection–deprotection steps, which are usually needed for regioselective alkylation of pyrimidine deoxynucleosides, can be avoided by choosing the appropriate solvent. The combined effects of low dielectric constant and possible sodium chelation by pyrimidine nucleosides may account for the unexpected regioselectivity observed in THF.
  • Keywords
    Regioselectivity , Nucleosides , Chelating agents , Alkylation
  • Journal title
    Carbohydrate Research
  • Serial Year
    2010
  • Journal title
    Carbohydrate Research
  • Record number

    966664

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=966664