Title of article
Revisiting the aldol reaction of cis-α,β-epoxyaldehyde promoted by BF3·Et2O: direct access to 2-deoxy-2-fluoro heptulosonic ester analogues Original Research Article
Author/Authors
Hatim Filali، نويسنده , , Mathieu Danel، نويسنده , , Stéphanie Ballereau، نويسنده , , Michel Baltas، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2010
Pages
6
From page
2421
To page
2426
Abstract
The aldol reaction between cis-3-((tert-butyldiphenylsilyloxy)methyl)oxirane-2-carbaldehyde and ethyl-2-(trimethylsilyloxy)-2-propenoate promoted by boron trifluoride diethyl etherate was reinvestigated. By varying the work-up conditions, a new 2-deoxy-2-fluoro heptulosonic ester analogue was synthesized. Derivatizations and detailed NMR analysis allowed the complete characterization of this fluoro analogue and its derivatives.
Keywords
Ulosonic acids analogues , Epoxyaldehyde , Fluorination , Aldol reaction , Boron trifluoride diethyl etherate
Journal title
Carbohydrate Research
Serial Year
2010
Journal title
Carbohydrate Research
Record number
966762
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