Title of article
CuAAC-mediated diversification of aminoglycoside–arginine conjugate mimics by non-reducing di- and trisaccharides Original Research Article
Author/Authors
Bernhard Westermann، نويسنده , , Simon D?rner، نويسنده , , Sebastian Brauch، نويسنده , , Angela Schaks، نويسنده , , Ramona Heinke، نويسنده , , Sebastian Stark، نويسنده , , Floris L. van Delft، نويسنده , , Sander S. van Berkel، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2013
Pages
7
From page
61
To page
67
Abstract
Di- and triguanidinylation of trehalose, sucrose, and melizitose has been achieved via a Huisgen-cycloaddition approach. They can serve as aminoglycoside–arginine conjugate mimics, which has been demonstrated by their biological profiles in assays against Bacillus subtilis. For comparative studies, tetraguanidinylated neamine and kanamycin derivatives have also been synthesized and evaluated.
Keywords
Aminoglycoside–arginine conjugate mimics , Guanidinylation , Click-reaction
Journal title
Carbohydrate Research
Serial Year
2013
Journal title
Carbohydrate Research
Record number
967857
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