Sequiterpene-related compounds as endocrine disrupters in Oncopeltus fasciatus, and potential reduced glutathione synthesis modifiers

Sesquiterpene lactones have been found to exhibit effects on insect growth and development. In this study, the bioactivity of natural lactones extracted from Centaurea mariolensis and some structurally related synthetic derivatives has been investigated. Assays have also been carried out in order to determine the potential of these lactones as modifiers of reduced glutathione GSH. synthesis.