18897

Synthesis a Novel Class of Unsaturated Cyclic Compounds Containing Phosphorus Atom Using Pseudo Four-Component Condensation Reactions

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A novel pseudo four-component condensation reaction for the efficient synthesis of 2ë5-[1,2]oxaphosphinin compounds using triphenylphosphine and ethyl bromoacetate in the presence of electron-deficient acetylenic esters without using any catalyst and activation is reported. Fully functionalized 2ë5-[1,2]oxaphosphinin derivatives can be prepared from simple and readily available precursors under neutral conditions.

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