Synthesis of New 4,5-dihydro-1 H--2-thiol Derivatives

In this work, 4,5-dihydro-lH-imidazole-2-thiol was prepared from ethylenediamine and then converted into 2-hydrazino-4,5- dihydro-1H-imidazole(2), Mannich bases (3-5), 4,5-dihydro-1Himidazole-2-ylamino )thio ]acetic acid ( 6), 2-alky lthio-4,5- dihydro- lH-imidazoles (7 and 8), 2-(-4,5-dihydro-1H-imidazolel- 2-yl-thio) acetamide (9), 2-[oxiran-2-ylmethy)thio]- 4,5- dihydro-lH-imidazole(l 0), 6,7-dihydro-5H-iidazo[2, 1-c] [1 ,2,4- ]triazole-3-amine (11) and azomethines (12-14). He azomethines (12-14) were converted to [1-acetyl-2-(4,5- dihydro-1 H-imidazo 1-2-yl) hydrazine ]( 4-bromophenyl)methylacetate ( 15), 2-( 4-aminophenyl)-3-( 4,5-dihydro-1 Himidazol- 2-ylamino-2- methyl-1 ,3-thiazoline-4-one(16) and N-[ chloro( 4-methoxyphenyl) me thy I]-N -4,5-dihydro- lHimidazol-2-yl-2 ,4-dinitrobenzohydrazide (17)