دراسة التاثير التثبيطي للمستخلص المائي الخام لاوراق نبات الكبر Capparis spinosa L. على الخط السرطاني Hep-2 و Hela

This study was conducted to know the inhibitory effect of the crude aqueous Capar, Capparis spaniosa leaf plant on two cellular cancer lines human epidermoid larynx carcinoma Hep-2 and human cervix uteri epitheloid carcinoma Hela .Four leaf extract concentrations have been used (125، 250،500 and1000) μg/ml and the exposure time was (48 and 72) hrs . This study indicated a clear significant inhibitory effect (p<0.001) of the extract on the cancer lines ،Hep-2 and Hela ،even with the first low concentration .The cellular Hep-2 density was (0.340%) , whereas the density in Hela was (0.6545%) at the lowest concentration 125 μg / ml . The highest inhibitory effect of the extract was at (1000) μg/ml ,the cellular Hep-2 density (0.108%) and in Hela (0.266%) . The highest significant inhibitory effect of the extract (72) hrs of exposure time was (0.275%) Hep-2 and (0.4624%) Hela The result of this study has indicated ahighest inhibitory activity of the aqucous leaf extract of Cpparis Spinosa on the density average of cancer cells for both Hep-2 and Hela . There was an inversely linear relation ship between exposure time and concentration on the . growth of cells . As exposure time and concentrations have increased , the killed cells have increased also .