تقييم صورة دهون مصل الدم في النساء قبل وبعد سن الياس في مدينة كركوك

Evaluation of lipid fractions in serum of premenopausal and postmenopausal women in Kirkuk city

The study aimed to investigate the levels of lipid fractions in the serum of premenopausal and postmenopausal women in Kirkuk city, because an alteration of there concentrations factors for incidence of cardiovascular disease . considered an important predisposing premenopausal women raged age 27- 45 years and 90 The study included 100 ranged age 51- 67 years. The blood samples were collected and postmenopausal women centerfuged for determination of total cholesterol( TC ) , triglyceride( TG ), low density lipoprotein( LDL-C ), high density lipoprotein( HDL-C), and very low density lipoprotein ( VLDL-C ) concentrations .The results of the study revealed no significant differences ( p>o.o5 ) for TC level, but there was a significant increase ( p<0.05 ) in the level of TG in postmenopausal women ( 143.13 ± 38.14 ) mg/dl When compared with the premenopausal women ( 102.88 ± 34.11gm/dl. While concentration of HDL-C recorded a significant decrease ( p<0.05 ) in postmenopausal women ( 33.01 ± 10.22 ) mg/dl, when compared with the premenopausal women ( 42.20 ± 15.24 ) mg/dl, also the same results recorded for LDL-C concentration ( 106.55 ± 23.2 ) mg/dl in postmenopausal women and ( 76.26 ± 32.06 ) mg/dl in premenopausal women. Whereas the significant increase ( p<0.05 ) in concentration of VLDL-C ( 31.63 ± 7.64 ) mg/dl in postmenopausal women when compared with the premenopausal women ( 20.58 ± 6.82 ) mg/dl. Finally we concluded that, there was a significant alterations in the level of lipid profile between premenopausal and postmenopausal women groups ,which were considered the most critical predisposing factor for incidence of cardiovascular disease in postmenopausal women.