متابعة سريرية لمعالجة التهاب النسج حول السنية الجائح الشاملة المدعومة بالميترونيدازول والاموكسيسيللين الجهازي

Background & Objective: The outcomes of aggressive peiodontitis therapy (AgP) are not always successful. The aim of the study is to assess the improvement of periodontal status of AgP after surgical periodontal therapy supported by systemic dosages of metronidazol and amoxicillin. Material & Methods: 26 patients mean age 22.39 years were selected at the department of periodontologyfaculty of dentistry- Damascus University. They were distributed into 2 groups: 15 patients exhibiting AgP (10female, 5meals) man age21.2 years and 11 (7 female, 4mal) mean age (23.41 years) healthy individual from their families .Probing depths (PD), clinical attachment loss (CAL) and papillae bleeding index (PBI) were performed for each individual. Periodontal therapy included mechanical, surgical therapy supported by dosage of Metronidazol 250mg/3 time daily and Amoxicillin 500 mg /4 times daily for a week after surgery. Mechanical medical therapies were repeated after 6 months and when PBI was more than 50%. T-test: Tow Samples Assuming Variance and tests was used for statistics p<0.05 ا Results: The statistical analysis showed significant differences P <0.05 for periodontal indices between 2 healthy and AgP groups, this did not include the numbers of teeth loss P>0.05. PD, CAL, PIB decreased significantly P<0.05 after 3 and 12 months of periodontal therapy in AgP group and with no statistical differences between 3 and 12 months P>0.05. No difference was observed also in PBI among the2 examined groups P>0.05 Conclusion: comprehensive periodontal therapy; mechanical and surgical supported by repeated dosage of Metronidazol and Amoxicillin have introduced improvement in AgP, but this did not reach the healthy status except of PBI.