Multi-component Synthesis of 1,4-dihydropyrano[2,3-c]pyrazoles in the presence of Co3O4@SiO2-NH2 nanocomposites as catalyst

In this research a series of pyranopyrazoles were efficiently synthesized via the one-pot fourcomponent reactions of ethyl acetoacetate hydrazinehydrate, aldehydes and malononitrile in the presence of Co3O4@SiO2-NH2 nanocomposites as catalyst. This study offers many advantages including short reaction times, excellent yields, environmental friendly nature, simple purification techniques and economic availability of the catalyst. The structure and magnetic characteristics of the nanocatalyst were fully characterized by spectral techniques including TEM,FE-SEM, EDX, XRD, FT-IR and VSM analysis.