Synthesis of novel hydrazone derivatives based on 4-methylcoumarin-7-yloxyacetohydrazide using catalytic amounts of zinc oxide nanoparticles

Some novel hydrazone derivatives of the 4-methylcoumarin-7-yloxyacetohydrazide was synthesized. Different acetophenone and benzaldehyde derivatives and 4-methylcoumarin-7-yloxyacetohydrazide were used as starting materials. The reaction was performed under reflux condition using zinc oxide nanoparticles as catalyst and ethanol as solvent. The reactions were monitored by tlc technique. Purification of the products afford the desired hydrazones in good to excellent yield.IR and NMR techniques were used for characterizing the products.