The one-pot synthesis of 14-aryl-14H-dibenzo [a,j] xanthene derivatives using nanoparticles of hydrogen sulfate ionic liquid immobilized on nanosilica

The synthesis of xanthenes, especially benzoxanthenes has attracted interest due to their biological and pharmaceutical properties such as antiviral, antibacterial, and antiflammatory. Various methods are available for the construction of xanthenes and benzoxanthenes.A novel and efficient procedure for the synthesis of 14-aryl-14H-dibenzo[a,j] xanthenes1 through One-Pot condensation of β-naphtol with benzaldehyde derivatives in aqueous media catalyzed by nanoparticles of hydrogen sulfate ionic liquid immobilized on nanosilica is described. An important advantage of this catalyst is the ease of separating it from the reaction mixture, as well as the fact that it could be recycled a number of times; mild conditions, excellent yield and short reaction time are other advantages of this catalyst as efficient and novel method.All reactions were monitored by TLC, and spectroscopic techniques such as 1HNMR and FT-IR, have been used to identify the products.