Preparation a Novel of Molecular Imprinted Nanoparticle Polymer for the Cancer Drug Delivery

The aim of the engineered drug delivery systems for cancer treatment is increasing the efficacy of chemotherapeutic agents while minimizing the interactions with healthy sites in the body [1]. This goal can be achieved by modifying their bio-distribution and controlling the rate at which the agent is released [2]. In this regard, different materials such as porous silica, carbon nanotube, calcium phosphate cement and various polymers have been intensively investigated in drugdelivery systems [3]. Herein, we would like to report preparation of the NIPAAM-functionalized MNPs (NIPAAM@Fe3O4)[4]addition of the DOX medicine to NIPAAM@Fe3O4, and preparation of the related polymer for delivery of DOX with the pH and thermosensitive properties.