Preparation and characterization of electrospun ZIF-8/PAN nanofiber for thin film microextraction of fluoxetine in aqueous samples

Metal-organic frameworks (MOFs) are a class of hybrid porous crystalline materials comprising of metal centers coordinated to organic linkers [1]. Owing to their well-defined pores and cavities in the scale of molecules combined with abundant surface chemistry, MOFs offer unprecedented opportunities for a wide range of applications including membrane-based separation [2]. In this work, the zeolitic imidazolate framework-8 (ZIF-8)/polyacrilonitrile (PAN) nanofiber was used in thin film microextraction procedure [3]. Firstly, the nanoparticles of ZIF-8 was synthesized [4] and different amounts (0-50%) of it were doped in 10% PAN solution and electrospun. Then the prepared nanofiber characterized using X-ray diffraction (XRD) patterns, field emission scanning electron microscopy (FESEM) images and Fourier transform-infrared spectroscopy (FT-IR). After that, this nanofiber was used as adsorption phase in thin film microextraction for fluoxetine extraction from aqueous sample. It was observed that, increasing the amounts of the doped ZIF-8 in the nanofiber enhanced the extraction efficiently linearly. Therefore the effect of ZIF-8 coatings on the extraction performance of TFME fiber was investigated. The developed nanofiber showed satisfactory extraction efficiency for the analyte and was successfully used in analyzing water samples.