Preparation of ZnFe2O4 nanoparticles using honey and its use as catalyst for the synthesis of 3-amino-4-cyano-5-phenyl-1H-pyrrole-2-carboxamides

This work described a green and useful method for the preparation of ZnFe2O4 nanoparticles using honey. This nano particles used as an efficient nanocatalyst for the synthesis of 3-amino-4-cyano-5-phenyl-1H-pyrrole-2-carboxamides. The synthesis was carried out via a simple three-component reaction between arylidenmalononitrile, malononitrile and hydroxylamine hydrochloride in the precense of nano ZnFe2O4 in solvent-free conditions. Eco-friendness method, short reaction times, excellent yields of products, inexpensive and readily available starting material, and time and energy saving are the main advantages of this method.