Determination of Thymol by NaY nanozeolite modified carbon paste electrode

Natural isopropyl cresols such as thymol (2-isopropyl-5-methylphenol) is credited with a series of pharmacological properties, including antimicrobial and antifungal effects. Thymol affect the surface electrostatics of the cell membrane and membrane integrity. Thymus pulegioides essential oil, consisting mainly of thymol, exhibits antifungal effects attributed to the formation of extensive membrane lesions and the reduction of ergosterol content [1]. Common methods was performed for quantification of thymol in different matrices including high performance liquid chromatography (HPLC) with different detection [2]. Zeolites are crystalline, porous solids whose intricate pore and channel systems in the molecular size range of 0.3 to about 1.5 nm are the basis for their immense importance in catalysis, separations, and ion exchange [3]. Zeolite Y can be viewed as the archetype zeolite owing to its enormous importance in catalysis (hydrocracking of petroleum) and its large stable pore structure, which makes it an ideal host for novel nanocomposites [3, 4]. In the present work, hydrothermally synthesis of NaY nanozeolite has been performed and characterized. Then, Mn(II)-exchanged Y nanozeolite were utilized for modification of carbon paste electrode (CPE) and applied for electrooxidation of thymol in phosphate buffer solution (pH = 10) using cyclic voltammetry technique.