Liquid phase microextraction based on deep eutectic solvent for extraction of agrochemical pesticides by gas chromatography

In the present work, a new class of solvent in the name of Deep eutectic solvent (DES) were synthesized and used as an extraction solvent in a headspace single drop microextraction method for the preconcentration and extraction of triazole pesticides from real sample by gas chromatography-flame ionization detection using choline chloride and 4-chlorophenol as deep eutectic solvent. Extraction was carried out by a hanging micro drop. The significant parameters HS-SDME process (type of solvent, drop volume, stirring speed, extraction temperature, sample pH and extraction time) were optimized. The limit of detection (LODs) calculated between 100 and 0.001 µgmL-1 with the relative standard deviation (RSD%) ranging from 4.3 to 8.2.