شماره ركورد كنفرانس
5328
عنوان مقاله
Computational design of aptamer-based biosensors for the detection of small molecule Toxins
پديدآورندگان
Salari Fatemeh sliftmh@gmail.com aDepartment of Chemistry, K. N. Toosi University of Technology, Tehran, Iran , Jalili Seifollah sjalili@kntu.ac.ir Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran, , Pakzadiyanc Atena a.pakzadiyan@email.kntu.ac.ir Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran
تعداد صفحه
2
كليدواژه
OBA3 aptamer , ochratoxin A (OTA) , ochratoxin B (OTB) , molecular dynamics (MD) simulations , biosensor
سال انتشار
1400
عنوان كنفرانس
بيست و سومين كنفرانس شيمي فيزيك انجمن شيمي ايران
زبان مدرك
انگليسي
چكيده فارسي
In this study, the interaction of OBA3 aptamer with two molecules, ochratoxin A (OTA) and ochratoxin B (OTB) was theoretically explored. To this end, molecular dynamics (MD) simulations on aptamer-OTA and aptamer-OTB complexes were applied to assess their ability in the development of aptamer-based biosensors.
كشور
ايران
لينک به اين مدرک