شماره ركورد كنفرانس
5536
عنوان مقاله
PLA/NMP system containing silica hybrids for bone tissue engineering
پديدآورندگان
Family Fereshteh fereshteh.family@aut.ac.ir Department of Polymer and Color Engineering, Amirkabir University of Technology, P.O. Box:15875-4413, Tehran, Iran , Mirzadeh Hamid Department of Polymer and Color Engineering, Amirkabir University of Technology, P.O. Box:15875-4413, Tehran, Iran , Bagheri-Khoulenjani Shadab Department of Polymer and Color Engineering, Amirkabir University of Technology, P.O. Box: 15875-4413, Tehran, Iran
تعداد صفحه
2
كليدواژه
tissue engineering , poly(lactic acid) , phase separation systems , biopolymer
سال انتشار
1401
عنوان كنفرانس
پانزدهمين همايش بين المللي علوم و فناوري پليمر
زبان مدرك
انگليسي
چكيده فارسي
In this study, an in situ forming (ISF) scaffold was investigated for the purpose of bone tissue engineering. Poly(lactic acid) (PLA) and N-methyl-2-pyrrolidone (NMP) based systems were prepared, and PLA chains were functionalized by an aminolysis treatment. The amine groups react with (3-Glycidyloxypropyl)trimethoxysilane (GPTMS), which is the coupling agent between the organic phase and silica network. The inorganic phase was prepared by sol-gel reaction using GPTMS and tetraethyl orthosilicate (TEOS). PLA-based systems were characterized using scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectra, and Ultraviolet-visible spectroscopy (UV-Vis). The results show that free amine groups ascent with HDA content and decrease with the formation of silica hybrids.
كشور
ايران
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