Author/Authors
yasmin, mohamad american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon , el sawd, jack american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon , gharamti, amal a. american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon , zmeter, carla american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon , khalifeh, riad american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon , kanafani, zeina a. american university of beirut - medical center - department of internal medicine, division of infectious diseases, Beirut, lebanon
Title Of Article
Herpes simplex virus-2 myelitis persistence of viral replication despite resolution of symptoms: Case report and review of the literature
شماره ركورد
18400
Abstract
Acute transverse myelitis, an acute inflammation of the spinal cord, can be caused by HSV infection. We report a case of an 85-year-old man who presented with lower extremity weakness and flare-up of a vesicular rash on the sacral area. The patient was diagnosed with acute transverse myelitis based on MRI and CSF findings. CSF analysis showed a lymphocytic pleocytosis and positive HSV-2 PCR. The patient was started on intravenous acyclovir, with full clinical and radiologic improvement despite persistence of HSV-2 PCR positivity in the CSF for four months. A review of the literature of HSV myelitis is included. We conclude that testing of HSV PCR on repeated CSF samples might not accurately reflect viral activity in the setting of clinical improvement.
From Page
57
NaturalLanguageKeyword
herpes simplex virus , myelitis, polymerase chain reaction
JournalTitle
Lebanese Medical Journal
To Page
60
JournalTitle
Lebanese Medical Journal
Link To Document