Author/Authors
Melek, Engin Cukurova University - Faculty of Medicine - Department of Pediatric Nephrology, Turkey , Atmış, Bahriye Cukurova University - Faculty of Medicine - Department of Pediatric Nephrology, Turkey , Bayazıt, Aysun Karabay Cukurova University - Faculty of Medicine - Department of Pediatric Nephrology, Turkey , Anarat, Ali Cukurova University - Faculty of Medicine - Department of Pediatric Nephrology, Turkey
Title Of Article
Linezolid-induced thrombocytopenia in two patients with renal dysfunction
شماره ركورد
24270
Abstract
Linezolid is an oxazolidinone antibiotic, active against gram-positive bacteria that are resistant to other antibiotics including glycopeptides. Thrombocytopenia is an adverse effect of linezolid. Although various risk factors have been suggested, the mechanisms behind this side effect are largely unknown. Here, we report two adolescents with the diagnosis of chronic kidney disease who developed thrombocytopenia following treatment with linezolid. Our purpose in highlighting these cases is to increase the clinical awareness concerning this side effect of linezolid. While it is well known that thrombocytopenia may develop during linezolid treatment, it is relatively unknown that patients with renal dysfunction have an increased risk for the development of thrombocytopenia compared to patients without renal dysfunction.
From Page
808
NaturalLanguageKeyword
Linezolid , thrombocytopenia , renal dysfunction
JournalTitle
Cukurova Medical Journal
To Page
810
JournalTitle
Cukurova Medical Journal
Link To Document