Blood vitamin D levels in patients with fibromyalgia and the effectiveness of vitamin D treatment

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Objective: The aim of this study was determination the level of vitamin D in patients diagnosed with fibromyalgia and investigation the relationship with etiopathogenesis of the disease. Methods: In this study, between the months of June and December in 2012, Metin Sabancı Bone Diseases Training and Research Hospital, Physical Therapy Outpatient Clinics, 141 patients diagnosed with fibromyalgia were included. The patients were diagnosed according to American College of Rheumatology criteria. Levels of C-reactive protein (CRP), serum calcium (Ca), phosphor (P), alkaline phosphatase (ALP), PTH, T3, T4, TSH, and vitamin D were analyzed in the blood of patients, for exclusion of a systemic illness. Deficiency of vitamin D is determined as ≤20 ng/ml and insufficiency of vitamin D is determined 21-29 ng/ml. Normal level of vitamin D is accepted as equal or ≥30 ng/ml. Results: The mean age of patients was found as 45.70±14.10 years old. Mean vitamin D level was 17.51±18.02 ng/ml. 76.6% (n=108) of all patients with fibromyalgia had vitamin D deficiency and their mean vitamin D level was detected as 12.23±10.24 ng/ml. Twenty (14.2%) of all patients had vitamin D insufficiency and their mean vitamin D level was found as 23.83±2.76 ng/ ml. The lower vitamin D level was seen in patients with age less than 45 years-old and their mean vitamin D level was 14.91±10.75 ng/ml. Conclusion: Vitamin D deficiency is frequently seen in patients diagnosed with fibromyalgia and treatment with vitamin D may cause regression of the disease.

585

D vitamin , fibromyalgia , calcium

Dicle Medical Journal

588

Dicle Medical Journal