Hypothyroidism in patients with obstructive sleep apnea syndrome

27087

Objective: In this study, we aimed to search the possible association between Obstructive Sleep Apnea Syndrome’s (OSAS) severity and thyroid gland malfunctions, and the effects of hypothyroidism on the mode of sleep in patients with OSAS. Methods: Demographic features and thyroid function tests of 211 patients (59, 28% female) with a mean age of 50.9 ± 10.4 years (ranging from 30 to 75) who underwent polysomnography between September 2010 and September 2011 were retrospectively evaluated. Results: Hypothyroidism was detected in 8.3% of the patients with simple snoring and 10.6% of those with OSAS (9.1% in mild OSAS, 20.3% in moderate OSAS and 6.3% in severe OSAS). There was no correlation between the severity of OSAS and the rate of hypothyroidism (p=0.620). The incidence of hypothyroidism was 16.9 % in women and 6.6% in men and this difference was statistically significant (p=0.024). The polysomnographic findings did not differ between the patients with hypothyroidism and the others (table 5). However, in patients with elevated TSH levels, the rate of desaturation during sleep was high despite a lower AHI (r=0.126, p=0.05). Conclusion: No correlation was seen between the severity of OSAS and the rate of hypothyroidism. Women with OSAS had higher incidence of hypothyroidism. The polysomnographic findings did not differ whether the patient had hypothyroidism or not. The rate of desaturation during sleep was relatively high in patients with elevated TSH levels.

512

Sleep , apnea , hypothyroidism

Dicle Medical Journal

517

Dicle Medical Journal