SPECIES DISTRIBUTION AND ANTIBIOTIC SUSCEPTIBILITIES OF ENTEROCOCCI STRAINS ISOLATED FROM URINE CULTURES

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OBJECTIVE: Enterococcal bacterial infections, which are the main cause of urinary tract infections and nosocomial infections, are known to cause serious and high mortality infections. The aim of this study was to investigate the antibiotic susceptibility and distribution of enterococci isolated from urine samples sent to the Medical Microbiology Laboratory from various outpatient clinics and services of Afyonkarahisar University of Health Sciences Hospital. MATERIAL AND METHODS: Between January 2014 and December 2018, microbiological methods were used for the isolation of bacteria from urine samples. VITEK 2 (bioMerieux, France) fully automated identification and antibiotic susceptibility system were used for identification and antibiotic susceptibility profile. Culture results were evaluated retrospectively. RESULTS: In our study, Enterococcus faecalis (69.1%) was the most common in this study. Enterococcus faecium (27.6%) was the second. Enterococci were most frequently observed in urine specimens sent from Physical Therapy and Rehabilitation (23%), Child Health and Disease (22.6%) and Urology Units (11.9%). Vancomycin resistance was 1.9% for Enterococcus faecalis and 6.3% for Enterococcus faecium. Ampisillin resistance was 83.9% for Enterococcus faecium, whereas this rate was determined to be 10.6% for Enterococcus faecalis. The rates of high-level gentamicin and streptomycin resistance were found to be 14.8%-6.2% for Enterococcus faecalis and 36.4%-10.5% for Enterococcus faecium, respectively. Penicillin resistance was found to be 4.8% for Enterococcus faecalis and 20.3% for Enterococcus faecium. CONCLUSIONS: In our study, antibiotics resistance of Enterococcus faecium and Enterococcus faecalis explains the treatment difficulties experienced in urinary tract infections. When the data from other studies and our study are examined, the rates of antibiotic resistance of enterococci differ according to the local in our country and regional in the world. Determination of local resistance profiles in enterococcal infections has a great importance in terms of treatment success and also to prevent the spread of these infections.

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Enterococcus , Urine culture , Antibiotic susceptibility

Kocatepe Medical Journal

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Kocatepe Medical Journal