Author/Authors
hoş, ayşegül sakarya university - department of biology, Sakarya, Turkey , tunç, kenan sakarya university - department of biology, Sakarya, Turkey
Title Of Article
ENHANCEMENT OF ANTIBACTERIAL EFFECTIVENESS OF AMOXICILLIN TRIHYDRATE AND AMPICILLIN-SULBACTAM
شماره ركورد
44953
Abstract
The improvement of antibacterial activity of antibiotics is an important issue because of the increase of multiple antibiotic resistant pathogen microorganisms. In this study, the synergistic effects of Punica granatum L. acetone fruit peel extract and antibiotics (Ampicillin-Sulbactam and Amoxicillin trihydrate) combinations were investigated. The disc diffusion method was used for the determination of the synergistic effect. Pomegranate acetone fruit peel extract and Amoxicillin trihydrate combination showed a synergistic effect against Escherichia coli, Staphylococcus aureus, Stapylococcus epidermidis, Salmonella typhimurium, Enterococcus faecalis, and Bacillus subtilis. Besides, the combination of P. granatum acetone fruit peel extract and Ampicillin-Sulbactam exhibited synergistic effect against S. epidermidis, E. faecalis, and B. subtilis. According to the results of this study, Punica granatum acetone fruit peel extract highly improved the antibacterial efficacy of Amoxicillin trihydrate and Ampicillin-Sulbactam.
From Page
92
NaturalLanguageKeyword
Synergy , Punica granatum , Amoxicillin trihydrate , Ampicillin , Sulbactam , Antibiotic
JournalTitle
Anadolu University Journal of Science and Technology C - Life Sciences and Biotechnology
To Page
97
JournalTitle
Anadolu University Journal of Science and Technology C - Life Sciences and Biotechnology
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