3-D phantom to simulate cerebral blood flow and metabolic images for PET

Author

Hoffman, E.J. ; Cutler, P.D. ; Digby, W.M. ; Mazziotta, J.C.

Author_Institution

Div. of Nucl. Med. & Biophys., California Univ. Sch. of Med., Los Angeles, CA, USA

Volume

37

Issue

2

fYear

1990

fDate

4/1/1990 12:00:00 AM

Firstpage

616

Lastpage

620

Abstract

A three-dimensional brain phantom has been developed to simulate the activity distributions found in the human brain in the cerebral blood flow and metabolism studies employed in PET (positron emission tomography). The phantom has a single contiguous chamber and utilizes thin layers of lucite to provide apparent relative concentrations of 5, 1, and 0 for grey matter, white matter, and ventricles, respectively, in the brain. The phantom and an ideal image set were created from the same set of data. Thus, the user has a basis for comparing measured images with an ideal image set, which enables the user to make quantitative evaluation of the errors in PET studies with a data set similar to that obtained in patient studies

Keywords

brain; computerised tomography; haemodynamics; radioisotope scanning and imaging; PET; activity distributions; cerebral blood flow; grey matter; lucite; metabolic images; patient studies; positron emission tomography; single contiguous chamber; thin layers; three-dimensional brain phantom; ventricles; white matter; Blood flow; Brain modeling; Humans; Imaging phantoms; Laboratories; Magnetic resonance imaging; Medical simulation; Nuclear medicine; Plastics; Positron emission tomography;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.106686

Filename

106686