DocumentCode
114816
Title
Finite element modeling of dielectrophoretic microelectrodes based on a array and ratchet type
Author
Buyong, Muhamad Ramdzan ; Abd Aziz, Norazreen ; Hamzah, Azrul Azlan ; Mohd Razip Wee, M.F. ; Majlis, Burhanuddin Yeop
Author_Institution
Inst. of Microeng. & Nanoelectronic (IMEN), Univ. Kebangsaan Malaysia (UKM), Bangi, Malaysia
fYear
2014
fDate
27-29 Aug. 2014
Firstpage
236
Lastpage
239
Abstract
This research describes an investigation of nonuniform electric field for dielectrophoretic forces (FDEP) application in particles and cells manipulation. In an electro kinetics occurrence, a miniaturized array and ratchet type microelectrodes has been simulated. The study of optimal FDEP behavior on the electric field distribution for both type microelectrodes was characterized and optimized by finite element method, (FEM). A set of array and ratchet type microelectrode are biased to generate asymmetric electric field distribution. Normalization of microelectrode simulation result shows that array and ratchet type produced a comparable electric field strength and direction. Deployment of additional dimension for array type electrode, three poles produced the highest of electric field strength of 7.513 e7 V/m and displacement field direction of 2.758 e-3 C/m2. Simulation results are used to design a higher sensitive and selective of a dielectrophoretic (DEP) microelectrode for selection, collection and processing of particle and cell using optimal FDEP that determination advancement in the development of dielectrophoretic a lab-on-a-chip. Ultimately, the findings of this work is possible to contribute in medical sciences research for the enrichment of stem cell from bone narrow and peripheral blood form via integration DEP into a lab on a chip, (DLOC) concept application.
Keywords
bioelectric potentials; biomedical electrodes; blood; bone; cellular biophysics; electrophoresis; finite element analysis; lab-on-a-chip; microelectrodes; FEM; asymmetric electric field distribution; bone narrow; cell manipulation; dielectrophoretic force application; dielectrophoretic microelectrodes; displacement field direction; electric field direction; electric field distribution; electric field strength; electrokinetic occurrence; finite element modeling; lab-on-a-chip; medical sciences research; microelectrode simulation; miniaturized array; nonuniform electric field; normalization; particle manipulation; peripheral blood; ratchet-type microelectrodes; stem cell enrichment; Arrays; Dielectrophoresis; Finite element analysis; Microelectrodes; Nonuniform electric fields; Microelectrode; dielectrophoretic; lab-on-a-chip;
fLanguage
English
Publisher
ieee
Conference_Titel
Semiconductor Electronics (ICSE), 2014 IEEE International Conference on
Conference_Location
Kuala Lumpur
Type
conf
DOI
10.1109/SMELEC.2014.6920840
Filename
6920840
Link To Document