Feature - Circuits and systems for high-throughput biology

High-throughput biological data acquisition and processing technologies have shifted the focus of biological research from the realm of traditional experimental science (wet biology) to that of information science (in silico biology). Powerful computation and communication means can be applied to the very large amount of apparently incoherent data coming from biomedical research. Part of the experiments and tests that we used to do in vitro and/or in vivo can now be done in silico. The concept of Laboratory (Lab) on Chip (LoC) is the natural evolution of System on Chip (SoC) by using an array of heterogeneous technologies. This paper reviews first hardware supports and technologies that allow the studies of whole bodies of molecules through the different steps of the biological information flow, and then some of the algorithms and softwares for data processing and integration