DocumentCode
1210249
Title
A Stimulator-Regulated Rapid-Freeze Clamp for Terminating Metabolic Processes of the Heart During Normal Physiological Working Conditions
Author
Wikman-Coffelt, Joan ; Coffelt, Robert J.
Author_Institution
Department of Agricultural Engineering, University of California, Davis, CA 95616, and the Cardiovascular Research Institute, University of California
Issue
6
fYear
1982
fDate
6/1/1982 12:00:00 AM
Firstpage
448
Lastpage
453
Abstract
A stimulator-regulated rapid-freeze clamp has been developed by which squeezing action is used to forge the physiologically functioning rat heart into a 0.5 mm thick wafer, thereby freezing (-80°C) the entire heart, and thus terminating metabolic processes in 5 ms ±0.5 ms at any defined point in the contraction cycle. The pneumatic cylinders contain large ports and frictionless seals. 80 psi of compressed air drives the anvils at an overall rate of 0.14 in/ms.
Keywords
Biochemical analysis; Catheters; Clamps; Employee welfare; Engine cylinders; Heart; Heat sinks; Heat transfer; Myocardium; Nitrogen; Animals; Electronics, Medical; Freezing; Heart; Myocardial Contraction; Myocardium; Perfusion; Rats;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.1982.324970
Filename
4121440
Link To Document