• DocumentCode
    1221683
  • Title

    Characterization of the Arterial System in the Time Domain

  • Author

    Laxminarayan, Swamy ; Sipkema, Pieter ; Westerhof, Nicolaas

  • Author_Institution
    Laboratory for Physiology, Free University
  • Issue
    2
  • fYear
    1978
  • fDate
    3/1/1978 12:00:00 AM
  • Firstpage
    177
  • Lastpage
    184
  • Abstract
    The impulse response function and the input impedance of the systemic arterial tree emphasize different aspects of this system. The impulse response function is calculated via inverse Fourier transformation of the input impedance. The effects of truncation of the impedance are reduced by subjecting the data to a Dolph-Chebyshev filter. The impulse response functions of a windkessel model, a uniform tube model, and of the arterial system of the dog, are given. The impulse response functions of the windkessel model and of the arterial system of the control dog show a sharp initial peak followed by an exponential decay (equal decay time as that of the diastolic pressure tracing). The height of the decay extrapolated to time zero is related to total arterial compliance. Total arterial compliance calculated in this way agrees with the value calculated from the ratio of the time constant of the diastolic pressure decay and peripheral resistance. The presence of peaks in the impulse response function indicates a distinct reflection site as shown in the uniform tube model and found in the dog with balloon occlusion of the descending aorta. The measurement of the time intervals between these peaks and the start of excitation together with the pulse wave velocity enable us to calculate the distance between the location of the reflecting site and the heart.
  • Keywords
    Control system synthesis; Electrical resistance measurement; Filters; Heart; Impedance; Pressure control; Pulse measurements; Reflection; Time measurement; Velocity measurement; Animals; Arteries; Biophysics; Dogs; Fourier Analysis; Hemodynamics; Models, Biological;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.1978.326244
  • Filename
    4122801