• DocumentCode
    1278129
  • Title

    CFD Modeling of an Ultrasonic Separator for the Removal of Lipid Particles From Pericardial Suction Blood

  • Author

    Trippa, Giuliana ; Ventikos, Yiannis ; Taggart, David P. ; Coussios, Constantin-C

  • Author_Institution
    Dept. of Eng. Sci., Univ. of Oxford, Oxford, UK
  • Volume
    58
  • Issue
    2
  • fYear
    2011
  • Firstpage
    282
  • Lastpage
    290
  • Abstract
    A computational fluid dynamics (CFD) model is presented to simulate the removal of lipid particles from blood using a novel ultrasonic quarter-wavelength separator. The Lagrangian-Eulerian CFD model accounts for conservation of mass and momentum, for the presence of lipid particles of a range of diameters, for the acoustic force as experienced by the particles in the blood, as well as for gravity and other particle-fluid interaction forces. In the separator, the liquid flows radially inward within a fluid chamber formed between a disc-shaped transducer and a disc-shaped reflector. Following separation of the lipid particles, blood exits the separator axially through a central opening on the disc-shaped reflector. Separator diameters studied varied between 12 and 18 cm, and gap sizes between the discs of 600 μm, 800 μm and 1 mm were considered. Results show a strong effect of residence time of the particles within the chamber on the separation performance. Different separator configurations were identified, which could give a lipid removal performance of 95% or higher when processing 62.5 cm3/min of blood. The developed model provides a design method for the selection of geometric and operating parameters for the ultrasonic separator.
  • Keywords
    biological fluid dynamics; biomedical ultrasonics; blood; computational fluid dynamics; confined flow; lipid bilayers; physiological models; ultrasonic transducers; CFD modeling; Lagrangian-Eulerian CFD model; computational fluid dynamics; disc-shaped reflector; disc-shaped transducer; fluid chamber; lipid particles; mass conservation; momentum conservation; particle-fluid interaction forces; pericardial suction blood; ultrasonic quarter wavelength separator; Acoustic transducers; Blood; Computational fluid dynamics; Computational modeling; Fluid flow; Gravity; Lagrangian functions; Lipidomics; Particle separators; Solid modeling; Computational fluid dynamics (CFD); lipid particles; radial flow; separation performance; ultrasonic separator; Blood Component Removal; Blood Transfusion, Autologous; Cardiac Surgical Procedures; Computer Simulation; Hemorheology; Humans; Lipids; Models, Cardiovascular; Pericardium; Transducers; Ultrasonics;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2010.2061845
  • Filename
    5530362