Effect of Frequency and Field Amplitude in Magnetic Hyperthermia

Author

Roca, A.G. ; Wiese, B. ; Timmis, J. ; Vallejo-Fernandez, G. ; O´Grady, K.

Author_Institution

Dept. of Phys., Univ. of York, York, UK

Volume

48

Issue

11

fYear

2012

Firstpage

4054

Lastpage

4057

Abstract

We have undertaken studies of the heating rate in three sets of magnetic nanoparticles for their application in magnetic hyperthermia. The nanoparticles were magnetite-maghemite with average particle diameters of 5, 28, and 45 nm, respectively. All samples were synthesized in an aqueous media and have a narrow size distribution. These sizes represent particles which are single domain, particles which lie close to the single domain multi-domain boundary, and particles which are probably multidomain. The heating rate is greater for the largest particles when an alternating magnetic field of 250 Oe and a frequency of 110 kHz are applied. The significant increase in heating for the 45 nm particles suggests that heating may be associated with particle rotation.

Keywords

biomagnetism; hyperthermia; iron compounds; magnetic domain walls; magnetic particles; nanofabrication; nanomagnetics; nanomedicine; nanoparticles; particle size; Fe₃O₄-Fe₂O₃; alternating magnetic ήeld; aqueous media; field amplitude effect; frequency 110 kHz; frequency effect; heating rate; magnetic hyperthermia; magnetic nanoparticles; magnetite-maghemite nanoparticles; narrow size distribution; particle rotation; particle size; single domain-multidomain boundary; size 45 nm; Heating; Hyperthermia; Magnetic domains; Magnetic hysteresis; Magnetic resonance; Materials; Nanoparticles; Domain wall motion; heating mechanisms; hyperthermia; magnetic nanoparticles;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2012.2201459

Filename

6332604