Threshold-distance measures from electrical stimulation of human brainstem

Author

Shannon, Robert V. ; Moore, Jean K. ; McCreery, Douglas B. ; Portillo, Franco

Author_Institution

House Ear Inst., Los Angeles, CA, USA

Volume

5

Issue

1

fYear

1997

fDate

3/1/1997 12:00:00 AM

Firstpage

70

Lastpage

74

Abstract

Threshold current levels for electrical stimulation of a single human brainstem via an auditory prosthesis are compared with postmortem measures of the distance between the electrode and stimulated structures. The results compare well with the summary of threshold-distance measures from animal experiments compiled by J. Ranck (see Brain Res., vol. 98, p. 417-40, 1975). The correspondence between the human and animal data gives confidence that the extent of current spread (distance to stimulable neural units) can be well estimated from the current level at threshold for 200 μs/phase biphasic pulses. This is of particular interest in electrical stimulation of the human central nervous system, where localization of stimulation is of paramount importance

Keywords

bioelectric phenomena; brain; hearing aids; prosthetics; 200 mus; animal experiments; auditory prosthesis; biphasic pulses; current spread; human brainstem electrical stimulation; human central nervous system; human data; postmortem measures; stimulable neural units; stimulation localization; threshold-distance measures; Animal structures; Central nervous system; Current measurement; Electric variables measurement; Electrical stimulation; Electrodes; Humans; Phase estimation; Prosthetics; Threshold current;

fLanguage

English

Journal_Title

Rehabilitation Engineering, IEEE Transactions on

Publisher

ieee

ISSN

1063-6528

Type

jour

DOI

10.1109/86.559351

Filename

559351