• DocumentCode
    1418268
  • Title

    Modeling Cellular Lysis in Skeletal Muscle Due to Electric Shock

  • Author

    Cela, Carlos J. ; Lee, Raphael C. ; Lazzi, Gianluca

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Univ. of Utah, Salt Lake City, UT, USA
  • Volume
    58
  • Issue
    5
  • fYear
    2011
  • fDate
    5/1/2011 12:00:00 AM
  • Firstpage
    1286
  • Lastpage
    1293
  • Abstract
    High-voltage electrical trauma frequently results in injury patterns that cannot be completely attributed to Joule heating. An electrical-injury model describing cellular lysis damage caused by supraphysiological electric fields is introduced, and used to evaluate the effects of high-voltage electric shock on the skeletal muscle of a human upper limb in a configuration that simulates hand-to-hand contact. A novel multiresolution admittance method, capable of efficiently handling large computational models while maintaining excellent accuracy, was used to perform the numerical computations. Values for the computed current through the arm and the upper limb impedance are reported.
  • Keywords
    biochemistry; biological effects of fields; biomedical measurement; cellular effects of radiation; electric admittance measurement; electric shocks; electrolysis; injuries; muscle; Joule heating; cellular lysis; electric shock effect; electrical-injury model; hand-to-hand contact; high-voltage electrical trauma; human upper limb; injury patterns; multiresolution admittance method; numerical computation; skeletal muscle; supraphysiological electric fields; Admittance; Conductivity; Electric shock; Injuries; Mathematical model; Muscles; Numerical models; Bioimpedance; electric shock; finite difference methods; injuries; multigrid methods; numerical simulation; Algorithms; Arm; Cell Death; Computer Simulation; Electric Injuries; Humans; Models, Biological; Muscle, Skeletal;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2010.2103362
  • Filename
    5680597