Bionanomanipulation Using Atomic Force Microscopy

Author

Xi, Ning ; Fung, Carmen Kar Man ; Yang, Ruiguo ; Seiffert-Sinha, Kristina ; Lai, King Wai Chiu ; Sinha, Animesh A.

Author_Institution

Electr. & Comput. Eng., Michigan State Univ., East Lansing, MI, USA

Volume

4

Issue

1

fYear

2010

fDate

3/1/2010 12:00:00 AM

Firstpage

9

Lastpage

12

Abstract

This paper explains how an AFM-based nanorobot was developed to visualize and quantify the dynamics of cell proteins interactions under physiological and pathophysiological conditions at the nanoscale. As these events are directly related at the molecular level to the causes of many life-threatening or incurable diseases, the development of an AFM-based nanorobot, which can image and manipulate biological objects at the single molecule level, is a novel approach to reveal disease markers and elucidate the disease mechanisms.

Keywords

atomic force microscopy; biomedical imaging; cellular biophysics; diseases; manipulators; medical robotics; molecular biophysics; nanobiotechnology; AFM; atomic force microscopy; bionanomanipulation; cell proteins interactions; diseases; nanorobot; pathophysiological conditions; physiological conditions; Atomic force microscopy; Diseases; Displays; End effectors; Force control; Force feedback; Haptic interfaces; Molecular biophysics; Nanobioscience; Visualization;

fLanguage

English

Journal_Title

Nanotechnology Magazine, IEEE

Publisher

ieee

ISSN

1932-4510

Type

jour

DOI

10.1109/MNANO.2010.935968

Filename

5430553