DocumentCode
1469040
Title
Multichannel Dosimeter and 
-Al 
O  of alumina is proposed for online in vivo dosimetry (IVD) in radiation therapy (RT). Two types of dosimetric-grade Al<sub>2</sub>O<sub>3</sub>:C crystals are compared and show different behavior according to manufacturing process. Metrological validations have been performed with a Saturne 43 LINAC in reference conditions at CEA LIST LNHB (French Ionizing Radiation Reference Laboratory). The dose response of OSL integrals under photon beam irradiation (6, 12, and 20 MV) show sublinearity behavior modeled by second-order equations and exhibit a small energy dependence (between 0.7% and 1.4%), explained by a modified intermediate cavity model adapted to a LINAC photon spectrum. Preclinical tests at Institut Gustave Roussy (IGR) prove that a proper design for a PMMA build-up cap leads to a low dependence vs photon beam orientation (± 1.5% and ± 0.9%) and vs field size in view of surface measurements.</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>Keywords</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>alumina; carbon; dosimetry; fibre optic sensors; linear accelerators; radiation therapy; α-Al<sub>2</sub>O<sub>3</sub>:C; Al<sub>2</sub>O<sub>3</sub>:C; CEA LIST LNHB; French ionizing radiation reference laboratory; LINAC photon spectrum; Saturne 43 LINAC; manufacturing process; metrological validations; modified intermediate cavity model; multichannel OSL fiber optic dosimeter; online in vivo dosimetry; optically stimulated luminescence fiber sensors; photon beam irradiation; photon beam orientation; radiation therapy; second-order equations; surface measurements; voltage 6 MV to 20 MV; Crystals; Optical fiber sensors; Optical fibers; Photonics; In Vivo Dosimetry (IVD); Optical Fiber Sensor (OFS); Optically Stimulated Luminescence (OSL); radiotherapy;</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>fLanguage</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>English</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>Journal_Title</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>Nuclear Science, IEEE Transactions on</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>Publisher</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>ieee</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>ISSN</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>0018-9499</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>Type</span></div><div class='col-12 col-md-9 leftDirection leftAlign'><h2 class='mb-0 fw-semibold'>jour</h2></div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>DOI</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>10.1109/TNS.2011.2114369</div></div>
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<div class='row g-0 align-items-center mb-2'><div class='col-12 col-md-3 fullRecLabelEnglish fw-bold mb-2 mb-md-0'><span class='text-muted small'>Filename</span></div><div class='col-12 col-md-9 leftDirection leftAlign'>5728895</div></div>
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<div class='row g-0 align-items-center'><div class='col-12 col-md-3 fw-bold mb-2 mb-md-0'><span class='text-muted small'>Link To Document</span></div><div class='col-12 col-md-9 leftDirection leftAlign'><a class='text-break' href='https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1469040' target='_blank' rel=)
https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1469040
https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1469040Multichannel Dosimeter and
https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1469040