Investigation of Size Dependence on Sensitivity for Nanowire FET Biosensors

Author

Ahn, Jae-Hyuk ; Choi, Sung-Jin ; Han, Jin-Woo ; Park, Tae Jung ; Lee, Sang Yup ; Choi, Yang-Kyu

Author_Institution

Dept. of Electr. Eng., Korea Adv. Inst. of Sci. & Technol., Daejeon, South Korea

Volume

10

Issue

6

fYear

2011

Firstpage

1405

Lastpage

1411

Abstract

Label-free electrical detection of biomolecules is demonstrated with a double-gate (DG) nanowire (NW) field-effect transistor (FET). Experimental results confirm that detection sensitivity is favorably improved by the increment of NW size in the DG-NWFET, whereas it is enhanced by the decrement of NW size in a conventional single-gate (SG) NWFET. Sensitivity improvement by the augmentation of the NW size in the DG-FET paves the way to overcome technical challenges we face in achieving ultimate miniaturization of the NW size in the SG-FET. This result is comprehensively understood by simple capacitive modeling. The proposed model explains the observed experimental data and provides a design guideline for highly sensitive NW biosensors.

Keywords

bioelectric potentials; biosensors; field effect transistors; molecular biophysics; nanobiotechnology; nanowires; biomolecules; capacitive modeling; detection sensitivity; double gate nanowire field effect transistor; label free electrical detection; nanowire FET biosensors; nanowire size; single gate NWFET; Biological system modeling; Biosensors; Capacitance; FETs; Logic gates; Sensitivity; Biosensor; capacitive model; double gate (DG); field-effect transistor (FET); nanowire (NW);

fLanguage

English

Journal_Title

Nanotechnology, IEEE Transactions on

Publisher

ieee

ISSN

1536-125X

Type

jour

DOI

10.1109/TNANO.2011.2157519

Filename

5773496