SPECT imaging with resolution recovery

Author

Bronnikov, Andrei V.

Author_Institution

Bronnikov Algorithms, Arnhem, Netherlands

fYear

2011

Firstpage

1

Lastpage

6

Abstract

Single-photon emission computed tomography (SPECT) is a method of choice for imaging spatial distributions of radioisotopes. Many applications of this method are found in nuclear industry, medicine, and biomedical research. We study mathematical modeling of a micro-SPECT system by using a point-spread function (PSF) and implement an OSEM-based iterative algorithm for image reconstruction with resolution recovery. Unlike other known implementations of the OSEM algorithm, we apply en efficient computation scheme based on a useful approximation of the PSF, which ensures relatively fast computations. The proposed approach can be applied with the data acquired with any type of collimators, including parallel-beam fan-beam, cone-beam and pinhole collimators. Experimental results obtained with a micro SPECT system demonstrate high efficiency of resolution recovery.

Keywords

collimators; image reconstruction; image resolution; medical image processing; optical transfer function; radioisotopes; single photon emission computed tomography; OSEM algorithm; OSEM-based iterative algorithm; SPECT imaging; biomedical research; computation scheme; cone-beam collimator; fan-beam collimator; image reconstruction; image resolution recovery; imaging spatial distributions; mathematical modeling; medicine research; microSPECT system; nuclear industry; parallel-beam collimator; pinhole collimator; point-spread function; point-spread function approximation; radioisotopes; resolution recovery; smgle-photon emissiophoton emissionn computed tomography; Collimators; Equations; Image reconstruction; Image resolution; Mathematical model; Phantoms; Single photon emission computed tomography; Single photon emission computed tomography (SPECT); image quality; nuclear medicine;

fLanguage

English

Publisher

ieee

Conference_Titel

Advancements in Nuclear Instrumentation Measurement Methods and their Applications (ANIMMA), 2011 2nd International Conference on

Conference_Location

Ghent

Print_ISBN

978-1-4577-0925-8

Type

conf

DOI

10.1109/ANIMMA.2011.6172966

Filename

6172966