Electrowetting of the blood droplet on the hydrophobic film of the EWOD chips

Author

Li, Lei ; Hu, Huan ; Lin, Hong ; Ye, Da-tian

Author_Institution

Dept. of Biomed. Eng., Tsinghua Univ., Beijing

fYear

2005

fDate

6/27/1905 12:00:00 AM

Firstpage

1941

Lastpage

1944

Abstract

Electrowetting-on-dielectric (EWOD) is a new method for handling droplets on the microfluidic chips. A most promising application for EWOD chips is the clinical diagnostics on human physiological fluids. This paper uses pure blood of rabbit as the experimental sample to test the wettability of the fluorocarbon polymer (p-C:F) hydrophobic layer of the EWOD chips. The contact angle variation of the blood droplet is observed, which provides the possibility of pure blood driven on the chips of p-C:F film. Forty multiple magnification images of the blood droplet are acquired by delicate experiments and the contact angles are calculated based on image processing technology. The electrowetting of the blood droplets on the EWOD chips is analyzed and the experimental results are in good agreement with the theoretical calculation

Keywords

bioMEMS; blood; contact angle; drops; lab-on-a-chip; microfluidics; patient diagnosis; polymer films; wetting; EWOD chips; blood droplet; clinical diagnostics; contact angle variation; electrowetting-on-dielectric; fluorocarbon polymer; human physiological fluids; hydrophobic film; image processing technology; microfluidic chips; multiple magnification images; pure blood of rabbit; Biomedical engineering; Blood; Humans; Image processing; Instruments; Microfluidics; Polymer films; Rabbits; Testing; Thermal engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1616832

Filename

1616832