• DocumentCode
    1648799
  • Title

    Simulation of adaptive control of lidocaine serum concentrations based on sparse measurements

  • Author

    Jannett, T.C. ; Geyer, J.D.

  • Author_Institution
    Alabama Univ., Birmingham, AL, USA
  • fYear
    1989
  • Firstpage
    262
  • Abstract
    Adaptive control of lidocaine serum concentrations based on sparse measurements is discussed. A model-based control law is used in conjunction with Bayesian parameter estimation to adjust the drug infusion rate to achieve and maintain a desired serum concentration. The performance of the system was assessed in Monte Carlo simulations over the range of pharmacokinetic parameters in the patient population
  • Keywords
    Bayes methods; Monte Carlo methods; adaptive control; biocontrol; blood; parameter estimation; physiological models; Bayesian parameter estimation; Monte Carlo simulations; adaptive control simulation; drug infusion rate; lidocaine serum concentrations; model-based control law; patient population; pharmacokinetic parameters; sparse measurements; Adaptive control; Bayesian methods; Biomedical measurements; Bismuth; Blood; Drugs; Length measurement; Parameter estimation; Predictive models; Time measurement;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
  • Conference_Location
    Seattle, WA
  • Type

    conf

  • DOI
    10.1109/IEMBS.1989.95712
  • Filename
    95712
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1648799