Hybridization of ODNs with core-shell structure of Fe3O4 nanoparticles and CSALG composite structure

Author

Chang, Ho ; Lin, LinWei

Author_Institution

Dept. of Mech. Eng., Nat. Taipei Univ. of Technol., Taipei, Taiwan

fYear

2010

Firstpage

854

Lastpage

855

Abstract

This study attempts to develop super-paramagnetic nanocomposite structure which have both magnetic and biocompatibility. With magnetic composite structure, nano-composite structure could be applied to bio-labeling, a specific tissue target detection and drug treatment. The author prepares Fe₃O₄ nanoparticles by chemical deposition. The diameter of the particle is about 20 nm, and is coated by CSALG complex membrane. Finally, the prepared nanocomposite structure undergone conjugating reaction with different types of ODNs are mixed in culturecell, so that they are linked together through the hybridization between different types of ODNs.

Keywords

biochemistry; biomagnetism; biomedical materials; iron compounds; magnetic particles; nanobiotechnology; nanocomposites; nanofabrication; nanoparticles; superparamagnetism; Fe₃O₄; bio-labeling; chemical deposition; conjugating reaction; drug treatment; hybridization; superparamagnetic nanocomposite structure; tissue target detection; Biomembranes; Chemical technology; DNA; Iron; Magnetic cores; Mechanical engineering; Nanobioscience; Nanoparticles; Nanostructures; Surface morphology;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanoelectronics Conference (INEC), 2010 3rd International

Conference_Location

Hong Kong

Print_ISBN

978-1-4244-3543-2

Electronic_ISBN

978-1-4244-3544-9

Type

conf

DOI

10.1109/INEC.2010.5425168

Filename

5425168