Micro-CT characterization of fusing extruded PCL scaffolds

Author

Darling, A. ; Shor, L. ; Khalil, S. ; Wang, F. ; Güçeri, S. ; Sun, W.

Author_Institution

Dept. of Mech. Eng. & Mech., Drexel Univ., Philadelphia, PA, USA

fYear

2003

Firstpage

166

Lastpage

167

Abstract

Micro-CT enables 3D characterization of the salient features of polymer scaffolds for tissue engineering applications. This paper presents our study on using micro-CT to evaluate the structural formability and the morphologies of PCL scaffolds fabricated by a Precision Extruding Deposition process. Results of as-fabricated scaffolds, with different processing parameters and micro-architectures were examined through micro-CT at 19.1 micron resolution. 2D analyses and 3D reconstructions of core regions of the sample scaffolds were performed. These results illustrate that qualitative and quantitative analysis of polymer scaffolds is possible through micro-CT and 3D reconstruction techniques.

Keywords

biological tissues; biomedical materials; computerised tomography; extrusion; image reconstruction; medical image processing; polymers; 3D reconstruction techniques; core regions; extruded PCL scaffolds fusion; micro-CT characterization; polymer scaffolds; processing parameters; sample scaffolds; tissue engineering; Fabrication; Image analysis; Image reconstruction; Mechanical factors; Microarchitecture; Morphology; Polymers; Sun; Testing; Tissue engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2003 IEEE 29th Annual, Proceedings of

Print_ISBN

0-7803-7767-2

Type

conf

DOI

10.1109/NEBC.2003.1216044

Filename

1216044