Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi

Author

Gur, Yigal S. ; Farncombe, Troy H. ; Pretorius, P. Hendrik ; Gifford, Howard C. ; Narayanan, Manoj V. ; Frey, Eric C. ; Gagnon, Daniel ; King, Michael A.

Author_Institution

Div. of Nucl. Medicine, Massachusetts Univ. Med. Center, Worcester, MA, USA

Volume

4

fYear

2001

fDate

6/23/1905 12:00:00 AM

Firstpage

2188

Lastpage

2192

Abstract

Scatter can be a confounding problem in the detection of perfusion defects in cardiac perfusion imaging. The goal of this investigation was to compare practical methods of scatter compensation representing different classes of compensation strategies. The methods investigated were: 1) modification of the energy window; 2) use of effective values of attenuation coefficients; 3) estimating the scatter distribution from energy spectrum information; and 4) estimating the scatter distribution in the spatial domain using the attenuation maps and scatter kernels. Monte Carlo simulated projections from two MCAT source distributions were used to investigate the impact of the various methods on residual scatter and cardiac uniformity. The investigation showed that each of the methods reduce the scatter significantly; however, the spatial domain method gave the least variation with the different source distributions and the best uniformity

Keywords

Monte Carlo methods; cardiology; image reconstruction; medical image processing; single photon emission computed tomography; technetium; MCAT source distributions; Monte Carlo simulated projections; SPECT acquisitions; Tc; Tc-99m labeled sestamibi; attenuation coefficients; attenuation maps; cardiac perfusion imaging; cardiac uniformity; compensation strategies; effective values; energy spectrum information; energy window; perfusion defects; residual scatter; scatter compensation; scatter compensation strategies; scatter distribution; scatter kernels; source distributions; spatial domain; spatial domain method; uniformity; Attenuation; Attenuators; Biomedical imaging; Heart; Imaging phantoms; Liver; Lungs; Monte Carlo methods; Scattering; Telephony;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2001 IEEE

Conference_Location

San Diego, CA

ISSN

1082-3654

Print_ISBN

0-7803-7324-3

Type

conf

DOI

10.1109/NSSMIC.2001.1009257

Filename

1009257