MRI-guided quantification of SPECT-images of the basal ganglia: a phantom study

Author

Koole, Michel ; Van de Walle, R. ; Van Laere, Koen ; Asseler, Yves D. ; Vandenberghe, Stefaan ; Bouwens, L. ; Lemahieu, Ignace ; Dierckx, Rudi

Author_Institution

MEDISIP, Ghent Univ., Belgium

Volume

1

fYear

2000

fDate

2000

Firstpage

476

Abstract

In this study, the authors present two methods for quantification of tracer uptake in a SPECT image, guided by a matched high-resolution structural MR image. The authors show preliminary results of both techniques, when applied for quantifying regional uptake in the different compartments of a phantom simulating the basal ganglia. These results indicate that the quantification method, which takes into account the blurring by the SPECT imaging device, promises to be more performant in the presence of background activity

Keywords

biomedical MRI; brain; image matching; image resolution; medical image processing; single photon emission computed tomography; MRI-guided quantification; SPECT-images; background activity; basal ganglia; medical diagnostic imaging; nuclear medicine; partial-volume correction; phantom study; Basal ganglia; High-resolution imaging; Image matching; Image segmentation; Imaging phantoms; Interpolation; Matrix converters; Parkinson´s disease; Pixel; Single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-6465-1

Type

conf

DOI

10.1109/IEMBS.2000.900779

Filename

900779