• DocumentCode
    1793971
  • Title

    Microassembly of spheroids by thermoresponsive gel probe

  • Author

    Takeuchi, Masaru ; Nakajima, Masahiro ; Fukuda, Toshio ; Hasegawa, Yohei

  • Author_Institution
    Dept. of Micro-Nano Syst. Eng., Nagoya Univ., Nagoya, Japan
  • fYear
    2014
  • fDate
    10-12 Nov. 2014
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    In this paper, manipulation of cell spheroids was conducted to construct 3D cell structures for tissue engineering applications. The spheroids were manipulated using thermoresposnive gel, and the cell viability was checked. The manipulated cells show more than 90 % viability. The results indicate that the spheroids can be assembled inside thermoresponsive polymer solution to construct 3D in vitro cell systems with keeping their live conditions.
  • Keywords
    cellular biophysics; intelligent materials; microassembling; pattern formation; polymer gels; thermodynamic properties; tissue engineering; 3D cell structure construction; 3D in vitro cell system construction; cell spheroid manipulation; cell spheroid microassembly; cell viability checking; live cell condition; thermoresponsive gel probe; thermoresponsive polymer solution; tissue engineering application; Assembly; Fluorescence; In vitro; Polymers; Probes; Three-dimensional displays; Tissue engineering;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro-NanoMechatronics and Human Science (MHS), 2014 International Symposium on
  • Conference_Location
    Nagoya
  • Print_ISBN
    978-1-4799-6678-3
  • Type

    conf

  • DOI
    10.1109/MHS.2014.7006124
  • Filename
    7006124