Assessment of Pulse Wave Velocity and Augmentation Index in different arteries in patients with severe coronary heart disease

Author

Hlimonenko, I. ; Meigas, Kalju ; Viigimaa, M. ; Temitski, K.

Author_Institution

Tallinn Univ. of Technol., Tallinn

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

1703

Lastpage

1706

Abstract

The aim of this study was to assess pulse wave velocity (PWV) and augmentation index in different arteries in patients with severe coronary heart disease (CHD). Signal measurements were obtained from 28 subjects. Severe coronary heart disease was confirmed by coronary angiography. Aortic PWV and augmentation Index were measured using the TENSIOMed Arteriograph. Four other pulse wave velocities (upper limb PWVx, upper limb PWV2, upper limb PWV3 and lower limb PWV) were obtained using PowerLab 4/20T device. It was found that aortic PWV was significantly increased in the CHD group compared with that in the control group (P<0.01). Augmentation index was significantly increased in the CHD group compared with the control group (P<0.01). This study shows the strong association of aortic stiffness and atherosclerosis. Pulse wave analysis can provide inexpensive and noninvasive means for studying changes in the elastic properties of the vascular system with the coronary heart disease.

Keywords

biomechanics; biomedical measurement; blood vessels; cardiovascular system; diagnostic radiography; diseases; elasticity; medical signal detection; velocity measurement; waveform analysis; PowerLab device; TENSIOMed Arteriograph; aortic stiffness; atherosclerosis; augmentation index; coronary angiography; coronary heart disease patients; pulse wave velocity assessment; signal measurements; upper limb pulse wave velocities; vascular elastic properties; Angiography; Arteries; Atherosclerosis; Blood pressure; Brachytherapy; Cardiac disease; Cardiology; Cardiovascular diseases; Reflection; Senior citizens; Adult; Aged; Aged, 80 and over; Aorta; Arteries; Blood Pressure; Coronary Angiography; Coronary Disease; Elasticity; Female; Humans; Male; Middle Aged; Pulsatile Flow; Pulse;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352637

Filename

4352637