DocumentCode
184274
Title
Lymph compartment models and HIV intra patient infection dynamics
Author
Knorn, Steffi ; Middleton, R.H.
Author_Institution
Signals & Syst. Group, Uppsala Univ., Uppsala, Sweden
fYear
2014
fDate
8-10 Oct. 2014
Firstpage
1699
Lastpage
1704
Abstract
A compartment model is proposed to describe the HIV infection in humans. The compartments describe the blood, several lymph nodes and connecting lymph vessels. The dynamics in each compartment are described by a simplified HIV model considering the healthy and infected T-cells. A bifurcation analysis based on the variation of the proliferation rate is discussed and supported by simulations. Additional simulations illustrate the effect of a simple mutation model.
Keywords
bifurcation; blood; blood vessels; cellular biophysics; diseases; HIV intrapatient infection dynamics; HIV model; bifurcation analysis; blood; connecting lymph vessels; healthy T-cells; infected T-cells; lymph compartment models; lymph nodes; mutation model; proliferation rate variation; Analytical models; Bifurcation; Blood; Human immunodeficiency virus; Lymph nodes; Mathematical model;
fLanguage
English
Publisher
ieee
Conference_Titel
Control Applications (CCA), 2014 IEEE Conference on
Conference_Location
Juan Les Antibes
Type
conf
DOI
10.1109/CCA.2014.6981557
Filename
6981557
Link To Document