DocumentCode
185702
Title
Application of immune algorithm in molecular docking
Author
Liu Zhen-yu ; Chen Ming-hua ; Kang Ling
Author_Institution
Dept. of Comput. Sci. & Technol., Dalian Neusoft Univ. of Inf., Dalian, China
fYear
2014
fDate
18-19 Oct. 2014
Firstpage
122
Lastpage
125
Abstract
As a kind of intelligent algorithm, the immune algorithm is improved from genetic algorithm by adopting the density adjusting mechanism to avoid from prematurity, and by good gene resaving mechanism to speed up convergence. To test the effectiveness of the algorithm, numerical example is first adopted; and then, the algorithm is applied into molecular docking, and gain better result than DOCK6_1.
Keywords
drugs; genetic algorithms; genetics; molecular biophysics; computer-aided drug molecule design; density adjusting mechanism; gene resaving mechanism; genetic algorithm; immune algorithm; intelligent algorithm; molecular docking; Convergence; Decision support systems; Encoding; Force; Genetic algorithms; Genetics; Radio frequency; Density adjustment; Good gene resaving mechanism; Immune algorithm; Molecular docking;
fLanguage
English
Publisher
ieee
Conference_Titel
Security, Pattern Analysis, and Cybernetics (SPAC), 2014 International Conference on
Conference_Location
Wuhan
Print_ISBN
978-1-4799-5352-3
Type
conf
DOI
10.1109/SPAC.2014.6982670
Filename
6982670
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